Acne Treatment

Overview

Acne is caused by the combined action of four factors: excess sebum production, abnormal keratinization of the follicular opening, proliferation of Cutibacterium acnes, and inflammatory response. Treatment follows a stepwise approach based on cause and severity, ranging from topical retinoids and antibiotics for mild cases to oral isotretinoin for severe cases, supplemented by laser therapy, chemical peeling, and LED therapy.

Mechanism

Treatment targets each pathogenic factor: topical retinoids normalize follicular keratinization and reduce microcomedones; benzoyl peroxide and antibiotics suppress C. acnes; oral isotretinoin dramatically reduces sebum production by shrinking sebaceous glands; chemical peels exfoliate the stratum corneum to unclog pores; laser and LED therapy reduce inflammation and stimulate healing. Combination therapy addressing multiple factors simultaneously yields the best outcomes.

Effects

Reduction of active acne lesions, prevention of new breakouts, sebum control, inflammatory calming, post-acne mark improvement, and long-term acne management.

Duration

Mild: 4-8 weeks; moderate: 2-3 months; severe (isotretinoin): 6-12 months; maintenance therapy ongoing as needed

Recovery

Topical treatments: mild dryness and peeling during initial adjustment. Laser/peeling: redness for 1-3 days. Isotretinoin: dryness of lips and skin throughout course. Most treatments allow normal daily activities.

Side Effects

Topical retinoids: dryness, peeling, initial purging. Isotretinoin: significant dryness, elevated liver enzymes, teratogenicity (pregnancy contraindicated). Laser: temporary redness and swelling. Treatment plan should be managed by a dermatologist.

Price Range

50,000-300,000 KRW per session (laser/peeling); oral medication costs separate

Target Audience

Those with persistent acne (inflammatory, comedonal, cystic), those not responding to over-the-counter products, and those seeking professional medical acne management.

Devices (2)